Problems in the Diagnostics and Treatment of Transtiretinum Amyloidosis with...
AbstractThe article presents a modern understanding of the treatment of cardiac amyloidosis and provides data on the frequency of occurrence, classification, and variants of clinical manifestations of...
View ArticlePeptide KE in Human Proteome
Peptide KE exhibits immunoprotective, geroprotective, and oncostatic activities and stimulates functional activity of fibroblasts. The KE motif is present in amino acid sequences of some cytokines and...
View ArticleComparison of the Effects of KE and AED Peptides on Functional Activity of...
We studied the effect of KE and AED peptides on the expression of sirtuin-1, sirtuin-6, collagen I, cytokines (IL-1, TGF-β), and transcription factor NF-κB in human skin fibroblasts during their...
View ArticleThymalin: Activation of Differentiation of Human Hematopoietic Stem Cells
Thymalin is a polypeptide complex isolated from the thymus and regulating the functions of the immune system. Thymalin is effective in therapy of acute respiratory syndrome, chronic obstructive...
View ArticleResults and Prospects of Using Activator of Hematopoietic Stem Cell...
AbstractThe paper presents the results of a standard and complex treatment method using the peptide drug thymus thymalin in patients with COVID-19. One of the mechanisms of the immunomodulatory effect...
View ArticlePeptide KED: Molecular-Genetic Aspects of Neurogenesis Regulation in...
Neuroprotective peptides are promising candidate molecules for the treatment of Alzheimer’s disease (AD). Oral application of KED (Lys-Glu-Asp) improved memory and attention in elderly individuals with...
View ArticleThe Use of Thymalin for Immunocorrection and Molecular Aspects of Biological...
AbstractThe polypeptide drug thymalin is used for various diseases associated with immune dysfunction, viral and bacterial infections, regeneration normalization, immunodepression, and the depression...
View ArticleAEDG Peptide Prevents Oxidative Stress in the Model of Induced Aging of Skin...
AbstractUltraviolet (UV) radiation is one of the main environmental factors leading to oxidative stress and accelerated skin aging. AEDG peptide, a regulator of pineal gland functions, has demonstrated...
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